Sentinel lymph node biopsy

Checking the first lymph nodes cancer would reach

Sources checked: September 2026

The short version

A sentinel lymph node biopsy identifies and removes the first one or few lymph nodes cancer cells would likely reach, to check whether cancer has spread there — often done at the same time as breast surgery.

A sentinel lymph node biopsy identifies the "sentinel" nodes — the first lymph nodes that fluid (and potentially cancer cells) would drain to from the tumor — using a tracer injected before surgery. These nodes are removed and examined; if they're free of cancer, it's often unnecessary to remove more nodes.

Removing only the sentinel nodes, rather than all the nodes under the arm, is generally associated with a lower risk of lymphedema (arm swelling) when the sentinel nodes are cancer-free.

Questions you may want to ask

  • Will this be done at the same time as my other breast surgery?

  • What happens if the sentinel nodes show cancer cells?

RelatedUnderstanding lymph node involvement

Sources